Journal of critical care
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Journal of critical care · Apr 2019
Mean arterial pressure during targeted temperature management and renal function after out-of-hospital cardiac arrest.
This study investigates the association between mean arterial pressure (MAP) and renal function after out-of-hospital cardiac arrest (OHCA). ⋯ Low mean MAP during TTM was independently associated with decreased renal function and need of renal replacement therapy in a large cohort of comatose OHCA-patients. Increasing MAP above the recommended 65 mmHg could potentially be renal-protective. This hypothesis should be investigated in prospective trials.
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Journal of critical care · Apr 2019
Risk factors for mortality and cost implications of complicated intra-abdominal infections in critically ill patients.
To assess risk factors for 28-day mortality and cost implications in intensive care unit (ICU) patients with complicated intra-abdominal infections (cIAIs). ⋯ IIAT and inadequate source control are confirmed predictors of mortality in ICU patients with complicated intra-abdominal infections. Empirical antimicrobial strategies and MDR may drive hospital costs.
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Journal of critical care · Apr 2019
Multicenter Study Observational StudyEpidemiology of disseminated intravascular coagulation in sepsis and validation of scoring systems.
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Journal of critical care · Apr 2019
The impact of psychological distress on long-term recovery perceptions in survivors of cardiac arrest.
To determine the association of depressive and PTSD symptoms with cardiac arrest survivors' long-term recovery perceptions, after accounting for cognitive status, functional independence, and medical comorbidities. ⋯ In contrast with cognitive and functional measures, depressive symptoms were strongly associated with cardiac arrest survivors' negative recovery perceptions at 6-months post-discharge.
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Journal of critical care · Apr 2019
Effects of antibiotic prophylaxis on ventilator-associated pneumonia in severe traumatic brain injury. A post hoc analysis of two trials.
To investigate the role of antibiotic prophylaxis (AP) in the incidence of ventilator-associated pneumonia (VAP) in patients suffering from traumatic brain injury (TBI). ⋯ Early use of AP delayed and may prevent the occurrence of VAP in severe TBI patients but did not change length of stay or mortality.