Journal of critical care
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Journal of critical care · Apr 2019
The impact of psychological distress on long-term recovery perceptions in survivors of cardiac arrest.
To determine the association of depressive and PTSD symptoms with cardiac arrest survivors' long-term recovery perceptions, after accounting for cognitive status, functional independence, and medical comorbidities. ⋯ In contrast with cognitive and functional measures, depressive symptoms were strongly associated with cardiac arrest survivors' negative recovery perceptions at 6-months post-discharge.
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Journal of critical care · Apr 2019
Risk factors for mortality and cost implications of complicated intra-abdominal infections in critically ill patients.
To assess risk factors for 28-day mortality and cost implications in intensive care unit (ICU) patients with complicated intra-abdominal infections (cIAIs). ⋯ IIAT and inadequate source control are confirmed predictors of mortality in ICU patients with complicated intra-abdominal infections. Empirical antimicrobial strategies and MDR may drive hospital costs.
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Journal of critical care · Apr 2019
Effects of antibiotic prophylaxis on ventilator-associated pneumonia in severe traumatic brain injury. A post hoc analysis of two trials.
To investigate the role of antibiotic prophylaxis (AP) in the incidence of ventilator-associated pneumonia (VAP) in patients suffering from traumatic brain injury (TBI). ⋯ Early use of AP delayed and may prevent the occurrence of VAP in severe TBI patients but did not change length of stay or mortality.
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Journal of critical care · Apr 2019
Comparative StudyLacosamide versus phenytoin for the prevention of early post traumatic seizures.
To compare the efficacy and safety of lacosamide versus phenytoin for seizure prophylaxis following TBI. ⋯ There was no difference between lacosamide and phenytoin in the prevention of early post traumatic seizures in patients following TBI. Lacosamide may have a more tolerable side effect profile.
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Journal of critical care · Apr 2019
Association of septic shock definitions and standardized mortality ratio in a contemporary cohort of critically ill patients.
The newly proposed septic shock definition has provoked a substantial controversy in the emergency and critical care communities. We aim to compare new (SEPSIS-III) versus old (SEPSIS-II) definitions for septic shock in a contemporary cohort of critically ill patients. ⋯ Compared to SEPSIS-II, SEPSIS-III definition of septic shock identifies patients further along disease trajectory with higher likelihood of poor outcome.