Journal of critical care
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Journal of critical care · Oct 2018
The evolution of activated protein C plasma levels in septic shock and its association with mortality: A prospective observational study.
Septic shock is commonly associated with hemostatic abnormalities. The endothelium-activated serine protease activated protein C (APC) plays a pivotal role in limiting coagulation and possesses anti-apoptotic and anti-inflammatory properties. We hypothesized that APC levels correlate with established coagulation parameters and provide prognostic information in patients with septic shock. ⋯ APC levels are increased in patients with septic shock and are correlated with established markers of coagulation. Elevated APC levels on admission are an independent predictor of mortality.
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Journal of critical care · Oct 2018
Bedside percutaneous dilatational tracheostomy in patients outside the ICU: a single-center experience.
To assess the safety of medical-ward bedside percutaneous dilatational tracheostomy (GWB-PDT). ⋯ GWB-PDT is a feasible and safe solution for tracheostomies in general-ward ventilated patients.
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Journal of critical care · Oct 2018
Association between the neutrophil-to-lymphocyte ratio and neurological outcomes in patients undergoing targeted temperature management after cardiac arrest.
This study aimed to elucidate the association between the neutrophil-to-lymphocyte ratio (NLR) and neurological outcomes in out-of-hospital cardiac arrest (OHCA) patients treated with targeted temperature management (TTM). ⋯ An NLR ≥ 6 at 72 h after the ROSC is associated with poor neurological outcomes at 6 months after CA.