Journal of critical care
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Journal of critical care · Jun 2018
Review Meta AnalysisReduced circulating B cells and plasma IgM levels are associated with decreased survival in sepsis - A meta-analysis.
B cell function and antibody production are crucial factors in host protection during inflammation. We aimed to synthesize the available evidence on the association between the reduction of circulating B cells and plasma immunoglobulin (IgM) levels and decreased survival during sepsis. ⋯ The protocol was registered (PROSPERO 2016:CRD42016053184).
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Journal of critical care · Jun 2018
ReviewCardiovascular ultrasonography detection of embolic sources in trauma.
Venous thromboembolism (deep vein thrombosis and pulmonary embolism) and bone cement implantation syndrome are major sources of embolic events in trauma patients. In these patients, embolic events due to venous thromboembolism and bone cement implantation syndrome have been detected with cardiac and vascular ultrasonography in the emergency setting, during the perioperative period, and in the intensive care unit. This article discusses the ultrasonography modalities and imaging findings of embolic events related to venous thromboembolism and bone cement implantation syndrome. The aim is to present a short review with exceptional illustrations that can enable physicians to identify sources of emboli in trauma patients with cardiovascular ultrasonography.
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Journal of critical care · Jun 2018
Sustained increase in angiopoietin-2, heparin-binding protein, and procalcitonin is associated with severe sepsis.
The identification of infection at its early stage in vulnerable patients is challenging. This study aimed to investigate potential biomarkers to distinguish patients progressing to severe sepsis from those with uncomplicated sepsis. ⋯ These findings indicated that sustained elevation of Ang-2, HBP, and PCT were associated with severe infection in critically ill patients.
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Journal of critical care · Jun 2018
Dead space analysis at different levels of positive end-expiratory pressure in acute respiratory distress syndrome patients.
To analyze the effects of positive end-expiratory pressure (PEEP) on Bohr's dead space (VDBohr/VT) in patients with acute respiratory distress syndrome (ARDS). ⋯ Increases in PEEP result in higher VDBohr/VT only when associated with an increase in driving pressure.