Journal of critical care
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Journal of critical care · Feb 2024
Observational StudyProspective evaluation of bleeding risk among thrombocytopenic patients admitted in intensive care unit.
Bleeding risk evaluation of thrombocytopenic patients admitted in ICU has been poorly investigated. ⋯ Plasma urea levels and the presence of skin purpura are helpful in identifying thrombocytopenic patients at high-risk of bleeding during ICU stay.
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Journal of critical care · Feb 2024
Observational StudyPlasma citrulline concentration and plasma LPS detection among critically ill patients a prospective observational study.
Gut can be a source of sepsis but sepsis itself can induce gut dysfunction. We aimed to study whether plasma citrulline, a marker of enterocyte mass, was correlated with plasma lipopolysaccharide, a potential marker of bacterial translocation among critically ill patients. ⋯ Plasma citrulline is not associated with the level of plasma LPS but is strongly decreased among septic patients. Detection of LPS is ubiquitous among critically ill patients but abdominal sepsis is associated with increased plasma LPS activity compared to extra-abdominal sepsis.
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Journal of critical care · Feb 2024
Comparison of various surrogate markers for venous congestion in predicting acute kidney injury following cardiac surgery: A cohort study.
Venous congestion has been demonstrated to increase the risk of acute kidney injury (AKI) after cardiac surgery. Although many surrogate markers for venous congestion are currently used in clinical settings, there is no consensus on which marker is most effective in predicting AKI. ⋯ Venous congestion is associated with AKI after cardiac surgery, but not necessarily with CRRT. Among the markers tested, IRVF exhibits the strongest correlation with AKI.