Journal of critical care
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Journal of critical care · Dec 2017
Multicenter StudyZika virus-induced neurological critical illness in Latin America: Severe Guillain-Barre Syndrome and encephalitis.
Zika virus (ZIKAV) is classically described as causing minor symptoms in adult patients, however neurologic complications have been recognized. The recent outbreak in Central and South America has resulted in serious illness in some adult patients. We report adult patients in Latin America diagnosed with ZIKAV infection admitted to Intensive Care Units (ICUs). ⋯ Differing from what was usually reported, ZIKAV infection can result in life-threatening neurologic illness in adults, including GBS and encephalitis. Collaborative reporting to identify severe illness from an emerging pathogen can provide valuable insights into disease epidemiology and clinical presentation, and inform public health authorities about acute care priorities.
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Journal of critical care · Dec 2017
Association between timing of intubation and outcome in critically ill patients: A secondary analysis of the ICON audit.
The optimal timing of endotracheal intubation in critically ill patients requiring invasive mechanical ventilation remains undefined. ⋯ In this large cohort of critically ill patients requiring intubation, intubation >2days after admission was associated with increased mortality later in the hospital course.
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Journal of critical care · Dec 2017
Observational StudyIntestinal fatty acid-binding protein level as a predictor of 28-day mortality and bowel ischemia in patients with septic shock: A preliminary study.
We sought to evaluate the levels of intestinal fatty acid-binding protein (I-FABP), a biomarker of enterocyte injury, as a predictor of 28-day mortality and bowel ischemia in septic shock patients. ⋯ I-FABP level at ICU admission can serve as a predictor of 28-day mortality in septic shock patients and is associated with the incidence of NOMI.
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Journal of critical care · Dec 2017
Development of a risk score to predict extubation failure in patients with traumatic brain injury.
To identify predictors and develop a risk score for the prediction of extubation failure in TBI patients. ⋯ The score developed to predict extubation failure in TBI patients can identify three risk categories and can be easily applied in the ICU.
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Journal of critical care · Dec 2017
Observational StudyImpact of restrictive fluid protocol on hypoxemia after aneurysmal subarachnoid hemorrhage.
In patients with aneurysmal subarachnoid hemorrhage (aSAH), acute cardiac dysfunction and triple-H-therapy, can lead to hypoxemia. Our aim was to assess impact of a protocoled fluid restrictive approach on hypoxemia in these patients. ⋯ Fluid restrictive management of patients with aSAH decreases number of hypoxemic patients at day 3 and day 7.