Journal of critical care
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Journal of critical care · Mar 2004
Randomized Controlled Trial Comparative Study Clinical TrialApplication of a cuirass and institution of biphasic extra-thoracic ventilation by gear-protected physicians.
To evaluate the speed by which cuirass application, followed by biphasic extra-thoracic ventilation, can be instituted by full anti-chemical protective gear-wearing physicians. ⋯ Physicians wearing full anti-chemical protective gear applied the cuirass and instituted biphasic extra-thoracic ventilation faster than ET intubation and manual positive pressure ventilation. Extra-thoracic ventilation should be further evaluated as an option for emergent respiratory support during toxic mass casualty events.
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Journal of critical care · Dec 2002
Randomized Controlled Trial Clinical TrialOccurrence of ventilator-associated pneumonia in mechanically ventilated pediatric intensive care patients during stress ulcer prophylaxis with sucralfate, ranitidine, and omeprazole.
The purpose of the study was to evaluate the effects of sucralfate, ranitidine, and omeprazole use on incidence of ventilatory-associated pneumonia (VAP) and mortality in ventilated pediatric critical care patients. ⋯ Our results did not show any difference in the incidence of VAP, macroscopic stress ulcer bleeding, and mortality in the mechanically ventilated PICU patients treated with ranitidine, omeprazole, or sucralfate, or nontreated subjects. None of the treatment regimens increased VAP compared with the nontreated group. Because there is insufficient data about stress ulcer prophylaxis and VAP in the pediatric age group, more studies with larger numbers of patients are needed.
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Journal of critical care · Mar 2002
Randomized Controlled Trial Clinical TrialAttitudes regarding organ donation from non-heart-beating donors.
To determine the attitudes toward organ donation from non-heart-beating cadaver donors in a sample of the general public and health care workers. ⋯ Both the general public and health care workers support the use of non-heart-beating cadaver donors once a decision has been made to withdraw life support. However, both groups raised concerns regarding how the decision to withdraw life support is made.
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Journal of critical care · Mar 2001
Randomized Controlled Trial Clinical TrialNutritional deficiencies and blunted erythropoietin response as causes of the anemia of critical illness.
The purpose of this article was to determine the prevalence of iron, vitamin B12, and folate deficiency and to evaluate the erythropoietin (EPO) response to anemia in a cohort of long-term intensive care unit (ICU) patients. ⋯ In this cohort, screening for iron, B12, and folate deficiency identified potentially correctable abnormalities in more than 13% of patients and should be considered in those who are anticipated to have long ICU stays. Even at an early point of critical illness, most patients had iron studies consistent with anemia of chronic disease (ACD), as well as a blunted EPO response that may contribute to this ACD-like anemia of critical illness.
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Journal of critical care · Jun 2000
Randomized Controlled Trial Clinical TrialEffect of an additional 1-hour T-piece trial on weaning outcome at minimal pressure support.
The purpose of this article was to investigate the effect of an additional 1-hour T-piece trial at the level of minimum pressure support (PSmin) on weaning outcome. ⋯ There were no advantages in weaning outcome by the addition of a 1-hour T-piece trial compared with prompt extubation at PSmin.