Journal of critical care
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Journal of critical care · Jun 2015
Change of hemopexin level is associated with the severity of sepsis in endotoxemic rat model and the outcome of septic patients.
The purpose of the study is to uncover the role of hemopexin (HPX) as anti-inflammatory mediator in animals and humans. ⋯ Low serum HPX levels are related to sepsis severity and could indicate poor prognosis for septic shock patients.
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Journal of critical care · Jun 2015
Review Meta AnalysisDoppler-based renal resistive index for prediction of renal dysfunction reversibility: A systematic review and meta-analysis.
Doppler-based renal resistive index (RI) might help in distinguishing transient from persistent acute kidney injury (AKI). The main objective of these systematic review and meta-analysis was to investigate the diagnostic performance of RI in predicting short-term reversibility of AKI. ⋯ These results suggest that an elevated RI may be a predictor of persistent AKI in critically ill patients. Further studies are warranted, however, to clarify the exact test performance given the marked heterogeneity among the included studies.