Journal of critical care
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Journal of critical care · Jun 2012
Multicenter StudyRisk factors for underuse of lung-protective ventilation in acute lung injury.
We assessed factors associated with underuse of lung-protective ventilation (LPV) in patients with acute lung injury (ALI). ⋯ Simple interventions could substantially improve adherence with LPV among patients with ALI and warrant prospective study.
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Journal of critical care · Jun 2012
Multicenter StudyThe adequacy of timely empiric antibiotic therapy for ventilator-associated pneumonia: an important determinant of outcome.
The individual impact of timeliness vs adequacy of empiric antibiotic therapy for a clinical suspicion of ventilator-associated pneumonia (CSVAP) is unknown. Accordingly, in patients with CSVAP and timely initiation of empiric antibiotic therapy, we determined the impact of inadequate therapy (IT). ⋯ In the context of early administration of empiric broad spectrum antibiotics for CSVAP, IT is associated with higher morbidity and mortality.
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Journal of critical care · Apr 2012
Multicenter Study Comparative StudyPlasma-Lyte 148 vs 0.9% saline for fluid resuscitation in diabetic ketoacidosis.
The purpose of the study was to determine the effects of Plasma-Lyte 148 (PL) vs 0.9% saline (NS) fluid resuscitation in diabetic ketoacidosis (DKA). ⋯ Patients with DKA resuscitated with PL instead of NS had faster initial resolution of metabolic acidosis and less hyperchloremia, with a transiently improved blood pressure profile and urine output.
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Journal of critical care · Apr 2012
Multicenter StudyBlood glucose amplitude variability as predictor for mortality in surgical and medical intensive care unit patients: a multicenter cohort study.
The aim of this study was to test the hypothesis that blood glucose amplitude variability (BGAV) is associated with mortality in critically ill patients. ⋯ Not all BGAV measures were associated with mortality. Blood glucose amplitude variability as quantified by SD was consistently independently associated with hospital mortality.
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Journal of critical care · Feb 2012
Multicenter Study Comparative StudyCritical care in Colombia: differences between teaching and nonteaching intensive care units. A prospective cohort observational study.
The aim of this study was to determine the differences in the efficacy and efficiency in providing critical care to hospitalized patients in teaching vs nonteaching intensive care units (ICUs) in Colombia. ⋯ Nonteaching ICUs discharge patients earlier than do teaching ICUs, but the effect of it remains to be clarified with further studies addressing questions as what happens after ICU discharge.