Journal of critical care
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Journal of critical care · Dec 2011
Multicenter StudyImpact of different types of organ failure on outcome in intensive care unit patients with acute kidney injury.
The aim of this study was to explore the impact of different types of associated organ failure in patients with acute kidney injury (AKI). ⋯ The prognosis of ICU patients with AKI depended on the total number and types of associated failed organ systems. Respiratory failure was the most common associated organ failure, but neurologic and hepatic failures were associated with the worst prognosis.
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Journal of critical care · Dec 2011
Randomized Controlled Trial Multicenter StudySevere protein C deficiency is associated with organ dysfunction in patients with severe sepsis.
The aim of this study was to assess the relationship between protein C levels and temporal changes in organ dysfunction. ⋯ Severe protein C deficiency in patients with severe sepsis is associated with both the incidence and severity of organ dysfunction and subsequent worsening of organ function and may be a useful predictor of organ failure in severe sepsis.
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Journal of critical care · Dec 2011
Multicenter StudyAcute kidney injury in critically ill patients with pandemic influenza A pneumonia 2009 in Korea: a multicenter study.
We assessed the incidence and clinical characteristics of acute kidney injury (AKI) in critically ill patients infected with pandemic influenza A (H1N1) and its effect on clinical outcomes. ⋯ A significant number of patients with H1N1-related critical illness developed AKI within 72 hours of ICU admission, and this early development of AKI was associated with 30-day mortality.
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Journal of critical care · Oct 2011
Multicenter Study Comparative StudyEvaluation of standard and modified severity of illness scores in the obstetric patient.
To test discrimination and calibration of APACHE-II and SAPS-II risk prediction scores in a cohort of obstetric patients, and to evaluate the effect of modifying these scores for the physiological changes in pregnancy. ⋯ APACHE-II and SAPS-II are good discriminators of illness severity and may be valuable for comparing obstetric cohorts, but APACHE-II significantly over-estimates mortality.
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Journal of critical care · Oct 2011
Multicenter StudyOutcome of reintubated patients after scheduled extubation.
The main objective of study was to evaluate the outcome of patients who require reintubation after elective extubation. ⋯ In a large cohort of scheduled extubated patients, one third of patients developed extubation failure, of whom half needed reintubation. Reintubation was associated with increased mortality due to the development of new complications after reintubation.