Journal of critical care
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Journal of critical care · Dec 2022
Randomized Controlled TrialMuscle size, strength, and physical function in response to augmented calorie delivery: A TARGET sub-study.
Augmented calories may attenuate muscle loss experienced in critical illness. This exploratory sub-study assessed the effect of augmented calorie delivery on muscle mass, strength, and function. ⋯ Augmented calorie delivery may not attenuate muscle loss or recovery of strength or function 6-months post-ICU, but this requires exploration in a larger trial.
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Journal of critical care · Dec 2022
The impact of obesity on the outcome of severe SARS-CoV-2 ARDS in a high volume ECMO centre: ECMO and corticosteroids support the obesity paradox.
The aim was to verify the impact of obesity on the long-term outcome of patients with severe SARS-CoV-2 ARDS. ⋯ The high incidence of obesity was not associated with worse short and long-term outcomes. ECMO in obese patients together with the use of steroids in the later stage of ARDS may improve survival.
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Journal of critical care · Dec 2022
Association between early, small creatinine elevation and severe acute kidney injury in critically ill adult patients.
Early prediction of AKI is crucial for critically ill patients. We investigated the association between small increase in creatinine and subsequent severe AKI in ICU patients. ⋯ Small creatinine elevation within the first 48 h of ICU admission was strongly associated with the AKI, kidney replacement therapy, and death. This association was more prominent in patients with normal baseline creatinine.