Archivos de bronconeumología
-
Arch. Bronconeumol. · Oct 2020
The Roles of Bacteria and Viruses in Bronchiectasis Exacerbation: A Prospective Study.
Exacerbations are crucial events during bronchiectasis progression. ⋯ Viral isolations, isolation of new bacteria and bacterial plus viral isolation are associated with bronchiectasis exacerbations. Symptoms at exacerbations might inform clinicians the possible culprit pathogens.
-
Arch. Bronconeumol. · Sep 2020
Gas Exchange and Ventilatory Efficiency During Exercise in Pulmonary Vascular Diseases.
Ventilatory inefficiency (high V'E/V'CO2) and resting hypocapnia are common in pulmonary vascular disease and are associated with poor prognosis. Low resting PaCO2 suggests increased chemosensitivity or an altered PaCO2 set-point. We aimed to determine the relationships between exercise gas exchange variables reflecting the PaCO2 set-point, exercise capacity, hemodynamics and V'E/V'CO2. ⋯ Resting hypocapnia is associated with worse cardiac function, more ventilatory inefficiency and reduced exercise capacity. This could be explained by elevated chemosensitivity and lower PaCO2 set-point. Maximal PETCO2 may be a useful non-invasive marker of PaCO2 setpoint and disease severity even with submaximal effort.