Archivos de bronconeumología
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Arch. Bronconeumol. · Jan 2009
Review[Annual review of Archivos de Neumología in interventional pneumology, interstitial diseases and lung transplantation].
A review has been made of original articles on invasive pneumology techniques, interstitial diseases and lung transplantation, published in the Archivos de Bronconeumología during the year 2008. We have selected the publication by Martínez-Olondrins et al on the mediastinal staging of bronchogenic carcinoma by
transbronchial needle aspiration to highlight the role of this simple, safe and cost-effective technique at a time when aspiration by ultrasound-guided bronchoscopy is profiled as an alternative to staging by mediastinoscopy. ⋯ In diffuse interstitial disease, Morell et al analysed the diagnostic methods in 500 patients with this clinical-radiological presentation in which a definitive diagnosis was achieved in 85%, with 25% of them being obtained by non-invasively. Baloira et al analysed the characteristics of 19 patients with desquamative interstitial pneumonia and respiratory bronchiolitis associated-interstitial lung disease obtained from the National register of Interstitial Diseases. -
Arch. Bronconeumol. · Jan 2009
Review[Key features in the management of diffuse interstitial pulmonary disease].
Diffuse interstitial lung disease is a heterogeneous group of diseases in which the common denominator is involvement of the area between the basement membrane of the alveolar epithelium and the capillary endothelium, known as the interstitial space. Diffuse interstitial lung disease poses a tremendous challenge to the clinician due to the diagnostic approach, the complications that can appear in the natural history of these entities, and the scarcity of available therapeutic resources. This brief review discusses key features of the management of diffuse interstitial pulmonary disease, such as prognostic factors, the therapeutic options -including the role of lung transplantation- and the diagnosis and treatment of two complications with crucial impact on the clinical course of the disease: exacerbations and associated pulmonary hypertension.
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Arch. Bronconeumol. · Dec 2008
Case Reports[Experience with imatinib to treat pulmonary arterial hypertension].
Despite advances in the treatment of patients with pulmonary arterial hypertension (PAH), survival has not improved greatly (is still very affected). Imatinib, an antagonist of platelet-derived growth factor with antiproliferative activity, has been effective in experimental models and clinically in several published reports. We report the results of imatinib therapy in 4 patients with PAH (functional class IV) who were refractory to treatment with drug combinations for this condition. ⋯ In this case, the patient was in functional class III and his hemodynamic parameters had improved significantly within 5 months after starting therapy. However, the patient died as a result of severe toxic hepatitis in which imatinib may have played a role. The present report adds to the few already in the literature (4 cases) and suggests that care should continue to be shown when using imatinib to treat PAH.
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Arch. Bronconeumol. · Nov 2008
Multicenter Study Comparative Study[Anesthesia in thoracic surgery in Catalonia: results of a survey carried out in 2003].
To determine the anesthetic, surgical, and postoperative characteristics of patients who underwent thoracic surgery in Catalonia, Spain, in 2003. ⋯ This survey provided information on anesthesia in thoracic surgery, which represented 0.7% of all anesthesia procedures in an area with a population of 7 million.