Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial Comparative Study Clinical Trial
Epidural morphine vs hydromorphone in post-caesarean section patients.
The purpose of this randomized controlled double blind study was to compare the efficacy of pain relief and the side effects of epidural hydromorphone and morphine in post-Caesarean patients. ⋯ Hydromorphone provides no clinical benefit over epidural morphine for post operative analgesia following Caesarean section.
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Randomized Controlled Trial Clinical Trial
Neuromuscular monitoring: does it make a difference?
The objective of the present prospective study was to evaluate the influence of neuromuscular monitoring on the level of neuromuscular blockade from induction of anaesthesia until extubation of the trachea. ⋯ The study demonstrates that with the same amount of vecuronium the neuromuscular relaxation was deeper with the use of a simple neuromuscular monitoring (visual evaluation of the thumb movements). Despite the deeper neuromuscular block in the monitored group, there was no residual curarization in the recovery room.
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Randomized Controlled Trial Comparative Study Clinical Trial
Acceleromyography improves detection of residual neuromuscular blockade in children.
To determine whether detection of residual blockade is improved by using the accelerograph. A secondary objective was to compare acceleromyographic measurements with those obtained by electromyography. ⋯ AMG is superior to visual assessment in detecting residual neuromuscular block and provides similar estimates of recovering block as the more cumbersome EMG.
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To describe the serum concentrations of ketamine following a clinically relevant dosing schedule during cardiopulmonary bypass (CPB). ⋯ This dosage regimen maintained general anaesthetic concentrations of ketamine throughout the operative period. These levels should result in brain tissue concentrations in excess of those previously shown to be neuroprotective in animals. Thus we conclude that this infusion regimen would be reasonable to be use in order to assess the potential neuroprotective effects of ketamine in humans undergoing CPB.