Canadian journal of anaesthesia = Journal canadien d'anesthésie
-
Randomized Controlled Trial Comparative Study Clinical Trial
Comparative effects of desflurane and isoflurane on recovery after long lasting anaesthesia.
Increasing the duration of exposure could lead to amplification of the pharmacokinetic differences between halogenated anaesthetic agents. The aim of our study was to compare anaesthesia recovery after desflurane and isoflurane, administered for more than three hours. ⋯ After long duration anaesthesia lasting up to three hours, desflurane allowed recovery and extubation in approximately half the time required by isoflurane. Less variability in results suggests better predictability of recovery with desflurane.
-
Clinical Trial Controlled Clinical Trial
Age related variability in the effects of mivacurium in paediatric surgical patients.
This study describes the effects of 0.3 mg.kg-1 mivacurium in 180 paediatric patients between the ages of one month and 13 yr. ⋯ The time course of block produced by mivacurium is more rapid in younger paediatric patients. The time course of mivacurium does not have the transatlantic variation which has been observed for vecuronium. Physiological changes suggestive of histamine release were frequent. Intubation conditions were very likely to be acceptable 90 sec after 0.3 mg.kg-1 mivacurium.
-
To review the experience of one tertiary care institution with somatosensory evoked potential (SSEP) monitoring during spinal surgery in order to assess the ability to monitor and predict neurological outcome effectively. ⋯ Effective SSEP monitoring was possible despite the many factors which may have interfered with monitoring. More improvements in the techniques and conditions of monitoring are needed to decrease the incidence of false positive and negative results.