Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial Comparative Study Clinical Trial
Ropivacaine vs bupivacaine in major surgery in infants.
To assess and compare the onset time and duration of neuroblockade obtained after ropivacaine or bupivacaine in infants undergoing major abdominal surgery. We also evaluated the efficacy and safety of employing ropivacaine instead of bupivacaine to provide operative anesthesia and postoperative analgesia. ⋯ In infants undergoing major abdominal surgery under combined epidural/light general anesthesia, ropivacaine 0.2% produces sensory and motor blockade similar in onset, duration of action and efficacy to that obtained from an equal volume, 0.7 ml x kg(-1), of bupivacaine 0.25%.
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Randomized Controlled Trial Comparative Study Clinical Trial
A comparison of thoracic and lumbar epidural techniques for post-thoracoabdominal esophagectomy analgesia.
To compare thoracic epidural analgesia (TEA) using a bupivacaine/fentanyl mixture and lumbar epidural analgesia (LEA) with morphine, in respect to the time to extubation and the quality of post-operative analgesia, in patients having thoracoabdominal esophagectomy. ⋯ This study has demonstrated superior pain control in patients undergoing thoraco-abdominal esophagectomy treated with TEA than with LEA, particularly for pain with movement. Tracheal extubation occurred earlier in the TEA group, but this difference was not significant at four hours postoperatively.
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Randomized Controlled Trial Clinical Trial
Reduced efficacy of simulated epidural test doses in sevoflurane-anesthetized adults.
To determine the hemodynamic responses to, and the efficacy of epinephrine-containing epidural test doses, during sevoflurane anesthesia, based on the conventional heart rate (HR) increase > or = 20 beats x min(-1), the modified HR increase if > or = 10 beats x min(-1), and the systolic blood pressure (SBP) increase 15 mmHg criteria. ⋯ During stable sevoflurane anesthesia, peak HR increase > or = 10 beats x min(-1) should be regarded as a positive response with end-tidal sevoflurane concentration < or = 1%, and peak SBP increase > or = 15 mmHg is applicable at sevoflurane concentrations between 0.5 and 2%.