Canadian journal of anaesthesia = Journal canadien d'anesthésie

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• Can J Anaesth · May 2012

  Comment

  Best evidence in critical care medicine. Early versus late parenteral nutrition in the adult ICU: feeding the patient or our conscience?

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• Can J Anaesth · May 2012

  Comparative Study

  Intrathecally administered ropivacaine is less neurotoxic than procaine, bupivacaine, and levobupivacaine in a rat spinal model.

  The aim of this study was to compare the neurotoxicity of intrathecal procaine, bupivacaine, levobupivacaine, and ropivacaine in an animal model. ⋯ All four local anesthetics seemed to cause identical neurotoxic lesions commencing in the PR and extending to the PC by axonal degeneration. Bupivacaine appeared to be the most neurotoxic of the four drugs, and the neurotoxicity at higher doses increased by volume with procaine > levobupivacaine > ropivacaine.

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• Can J Anaesth · May 2012

  Biography Historical Article

  Remembering David Shephard, MB FRCPC (1930-2011).

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• Can J Anaesth · May 2012

  Editorial Comment

  Correct positioning of double-lumen tubes.

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