Canadian journal of anaesthesia = Journal canadien d'anesthésie
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Randomized Controlled Trial Clinical Trial
Oral midazolam premedication in children: the minimum time interval for separation from parents.
To determine the minimum time interval between oral midazolam (0.5 mg.kg-1) premedication and separation from parents that ensures a smooth separation, 30 children were assigned randomly to one of three groups (ten children per group). The groups differed only in the time interval between administration of midazolam and separation from their parents: 10, 20 or 30 min. Heart rate, systolic blood pressure, and sedation and anxiolysis scores were assessed before midazolam premedication (baseline), at the time of separation from parents, and during the application of a face mask at the induction of anaesthesia. ⋯ Sedation scores at separation did not differ among the three groups. Anxiolysis values did not differ from baseline values at any time for all three groups. We conclude that children may be separated from their parents as early as ten minutes after receiving oral midazolam, 0.5 mg.kg-1.
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To determine the publication rate of abstracts as peer-reviewed manuscripts during the five years subsequent to their presentation, the rates of publication of abstracts that were presented at meetings of four anaesthesia societies (American Society of Anesthesiologists (ASA), International Anesthesia Research Society (IARS), Anaesthesia Research Society (ARS) and Canadian Anaesthetists' Society (CAS), in 1985 were determined. Abstracts (total = 215) from each of the four meetings were selected (ASA n = 114/573 total, IARS n = 39/119, ARS n = 33/99 and CAS n = 29/58) and their appearances in the literature as peer-reviewed manuscripts were determined using MEDLINE for the years 1985 to 1990 under the surname of the presenting author. The contents of the abstracts were compared with those of the resultant manuscripts. ⋯ The proportions of abstracts that were published as manuscripts from the four societies were similar. Of the abstracts that were published as manuscripts, 13% from the ASA, 16% from the IARS, 16% from the ARS and 0% from the CAS were published four or five years after abstract presentation. Although the overall proportion of abstracts that was published within five years of presentation did not differ from the rate of publication within three years, we recommend that a uniform policy with respect to the time interval for citation of abstracts be adopted for all anaesthesia journals.
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A case is presented of a 33-yr-old parturient with Harrington fusion of her spine who received spinal anaesthesia with 15 mg hyperbaric bupivacaine for Caesarean delivery. Multiple attempts of needle insertion in both midline and paramedian at the L3-4 interspace were unsuccessful, whereas the procedure was performed uneventfully at the midline of the L5S1 interspace. The anatomical considerations and difficulties in achieving reliable epidural anaesthesia after Harrington fusion are reviewed. Spinal anaesthesia performed at the L5S1 interspace may provide less technical difficulty and a more reliable result in such patients.