Canadian journal of anaesthesia = Journal canadien d'anesthésie
The most recent articles from:
Can J Anaesth
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Randomized Controlled Trial
A randomized-controlled trial of nabilone for the prevention of acute postoperative nausea and vomiting in elective surgery.
Nabilone is a synthetic cannabinoid with properties that make it an appealing candidate as a postoperative nausea and vomiting (PONV) prophylactic adjunct. Nabilone has proven clinical utility in chemotherapy-related nausea and vomiting but has not been adequately tested for PONV. The purpose of this study was to evaluate the effectiveness of a single dose of nabilone for the prevention of PONV. ⋯ Oral nabilone 0.5 mg given as a single dose prior to surgery is ineffective in reducing PONV. This trial was registered at ClinicalTrials.gov, identifier: NCT02115529.