The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Mar 1998
The clinical spectrum of respiratory syncytial virus disease in The Gambia.
Respiratory syncytial virus (RSV) is a well-recognized cause of lower respiratory tract infections in early childhood in industrialized countries, but less is known about RSV infection in developing countries. ⋯ RSV is a significant cause of lower respiratory tract infection in young children in The Gambia, causing epidemics of bronchiolitis. It poses a significant burden on the health system, especially through the demand for supplementary oxygen. The clinical spectrum of RSV disease in The Gambia is similar to that seen in developed countries; concomitant bacterial infections are uncommon.
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Pediatr. Infect. Dis. J. · Feb 1998
Sepsis during total parenteral nutrition: exploration of risk factors and determination of the effectiveness of peripherally inserted central venous catheters.
Sepsis is the most frequent serious complication during total parenteral nutrition (TPN), resulting in increased morbidity, mortality and health care costs. Existing reports have not documented the risk factors of sepsis during TPN. The objectives of this study were to determine the rate of sepsis in our practice and to explore the risk factors for sepsis during TPN. We also determined the role and efficacy of using peripherally inserted central venous catheters (PCVC) as insertion catheters to administer TPN. ⋯ Considering the high incidence of sepsis during TPN, every attempt should be made to minimize the length of TPN therapy and encourage early enteral feeding. We also recommend the use of PCVC in patients requiring prolonged nutritional support.
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Pediatr. Infect. Dis. J. · Jan 1998
Transmission of cytomegalovirus to preterm infants through breast milk.
To evaluate the rate of virus excretion through breast milk and the incidence and significance of postnatal cytomegalovirus (CMV) transmission from mothers to premature infants. ⋯ In mothers of preterm infants a high incidence of CMV excretion into breast milk was detected. There is evidence that the most immature infants are at the greatest risk to acquire an early and symptomatic CMV infection.
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Pediatr. Infect. Dis. J. · Aug 1997
A prospective study of neonatal sepsis and meningitis in southern Israel.
To study the epidemiology of neonatal sepsis and meningitis in the Negev area of southern Israel. ⋯ Neonatal sepsis and meningitis rates in southern Israel are similar to those reported in Western Europe and the United States. The incidence of neonatal sepsis is significantly higher for Bedouins than for Jewish neonates. The distribution of the main pathogens is different in southern Israel and although Gram-negative enteric organisms are predominant, S. agalactiae plays a relatively minor role in the etiology of sepsis during the first month of life. In southern Israel the etiology of community-acquired late onset sepsis is different from that of nosocomial late onset sepsis.