The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Sep 2006
Randomized Controlled Trial Clinical TrialEffectiveness of heptavalent pneumococcal conjugate vaccine in children younger than 5 years of age for prevention of pneumonia: updated analysis using World Health Organization standardized interpretation of chest radiographs.
A World Health Organization (WHO) working group in 2001 developed a method for standardizing interpretation of chest radiographs in children for epidemiologic purposes. We reevaluated radiographs from the Kaiser Permanente Pneumococcal Efficacy trial using this method. ⋯ Using WHO criteria for reading of radiographs increased point estimates of vaccine efficacy presumably as a result of improved specificity.
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Pediatr. Infect. Dis. J. · Sep 2006
Adenoviral infections in pediatric transplant recipients: a hospital-based study.
To assess the disease burden and outcomes resulting from adenoviral infections among pediatric transplant recipients. ⋯ Mortality from adenoviral infection was a greater risk for HSCT than SOT recipients. Early onset of infection after transplantation suggests the possibility of reactivation of adenovirus rather than new acquisition in at least of proportion of cases. This is important for surveillance of this infection in transplant recipients.