The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Aug 2003
Comparative StudyPredictors of neonatal sepsis in developing countries.
Neonatal infections are a major cause of death worldwide. Simple procedures for identifying infants with infection that need referral for treatment are therefore of major public health importance. ⋯ Physical signs can be used to identify young infants at risk of severe disease, however with limited specificity, resulting in large numbers of unnecessary referrals. Further studies are required to validate and refine the prediction of severe disease, especially in the first week of life, but there appear to be limits on the accuracy of prediction that is achievable.
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Pediatr. Infect. Dis. J. · Aug 2003
Letter Case ReportsSystemic meningococcal infection and complement deficiency.
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Pediatr. Infect. Dis. J. · Jul 2003
Comparative StudyClindamycin treatment of invasive infections caused by community-acquired, methicillin-resistant and methicillin-susceptible Staphylococcus aureus in children.
Community-acquired, methicillin-resistant Staphylococcus aureus (CA-MRSA) is an established pathogen in several areas of the United States, but experience with clindamycin for the treatment of invasive MRSA infections is limited. We compared the outcome of therapy for MRSA with that of methicillin-susceptible (MSSA) invasive infections in children treated with clindamycin, vancomycin or beta-lactam antibiotics. ⋯ Clindamycin was effective in treating children with invasive infections caused by susceptible CA-MRSA isolates.
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Pediatr. Infect. Dis. J. · Jun 2003
Case ReportsParalytic poliomyelitis caused by a vaccine-derived polio virus in an antibody-deficient Argentinean child.
We describe a case of poliomyelitis in a 3-year-old Argentinean boy with X-linked hypogammaglobulinemia. The child had no history of polio vaccination, but a poliovirus isolated from a stool sample had 97.2% genetic similarity to the Sabin 1 vaccine strain. According to the WHO definition, this is the first case reported of a vaccine-derived poliovirus infection recorded in continental Latin America.