The Pediatric infectious disease journal
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Pediatr. Infect. Dis. J. · Mar 2003
Comparative StudyIntussusception-associated hospitalization among Venezuelan infants during 1998 through 2001: anticipating rotavirus vaccines.
The first licensed rotavirus vaccine was withdrawn from use in the United States because of a low risk of intussusception. Consequently tests of new rotavirus vaccines will require some baseline knowledge of the rates and treatment of intussusception in countries where these vaccines will be tested. Therefore the objective of this study was to assess hospitalization rates and describe the epidemiologic and clinical characteristics of intussusception in Carabobo, Venezuela. ⋯ This study provides some data about the incidence of intussusception and its epidemiology in a developing country where current or future field trials with rotavirus vaccine will be conducted.
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Pediatr. Infect. Dis. J. · Feb 2003
Review Case ReportsCapnocytophaga canimorsus meningitis in a newborn: an avoidable infection.
Capnocytophaga canimorsus causes dog-bite wound induced sepsis in adults, but infection may follow mucous membrane exposure. Systemic infection in children is extremely rare. ⋯ Suspicion of this pathogen requires laboratory consultation. Parental counseling can limit the risk of pet acquired infections.
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Pediatr. Infect. Dis. J. · Feb 2003
ReviewRespiratory syncytial virus bronchiolitis: supportive care and therapies designed to overcome airway obstruction.
Treatment of respiratory syncytial virus bronchiolitis rests primarily on supportive care with oxygen and fluid management. Other therapies commonly used include bronchodilators, corticosteroids and ribavirin, when considered appropriate. ⋯ Management of bronchiolitis can be facilitated by (1) recognizing the risks and benefits of various therapies, (2) understanding the markers of disease severity and (3) gaining familiarity with the time course of viral replication compared with presentation of symptoms. Although oxygen administration and judicious fluid replacement are the only interventions proved to be of reliable benefit to infants with bronchiolitis, newer studies support a role for adjunctive therapies aimed at relieving airway obstruction, especially when administered very early in the course of the illness or given to infants with more severe disease.