Critical care medicine
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Critical care medicine · Oct 1995
Comparative Study Clinical Trial Controlled Clinical TrialEffect of heparin on whole blood activated partial thromboplastin time using a portable, whole blood coagulation monitor.
To evaluate the responsiveness of whole blood activated partial thromboplastin time (aPTT) to varying heparin doses in vitro and to examine the ex vivo relationship of whole blood aPTT to plasma heparin concentration. ⋯ Heparin responsiveness of whole blood aPTT, measured with a portable whole blood coagulation monitor, is similar to that of conventional laboratory aPTT over a clinically relevant range of heparin concentrations in vitro and ex vivo. On-site whole blood aPTT measurements should be useful in clinical situations requiring rapid aPTT results.