Critical care medicine
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Critical care medicine · Jan 1998
Randomized Controlled Trial Comparative Study Clinical TrialArtificial nutrition after major abdominal surgery: impact of route of administration and composition of the diet.
To evaluate the impact of the route of administration of artificial nutrition and the composition of the diet on outcome. ⋯ Early enteral feeding is a suitable alternative to TPN after major abdominal surgery. The use of the enriched diet appears to be more beneficial in malnourished and transfused patients.
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Critical care medicine · Jan 1998
Comparative StudySerial determinations of cerebral water content by magnetic resonance imaging after an infusion of hypertonic saline.
To determine regional cerebral water content in vivo by magnetic resonance imaging (MRI) after the administration of 7.5% saline in brain-lesioned rabbits. ⋯ The administration of a 7.5% saline solution causes a prompt and substantial decrease in cerebral water content as assessed by spin-echo T2-weighted MRI. Magnetic resonance imaging offers the opportunity for repeated, noninvasive in vivo determinations of cerebral water content.
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Critical care medicine · Jan 1998
Plasma nitrite and nitrate concentrations and multiple organ failure in pediatric sepsis.
To determine whether plasma nitrite and nitrate concentrations are associated with the development of sepsis-induced multiple organ failure. ⋯ Increased plasma nitrite and nitrate concentrations are associated with the development of multiple organ failure in pediatric sepsis.
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Critical care medicine · Jan 1998
Comparative StudyAcute exacerbations of chronic obstructive pulmonary disease and mechanical ventilation: a reevaluation.
To review the intensive care unit (ICU) experience of patients admitted with acute exacerbations of chronic obstructive pulmonary disease. ⋯ ICU admission of severely ill chronic obstructive pulmonary disease patients results in acceptable outcomes. Survival of < or =2 yrs is not affected by mechanical ventilation or tracheostomy requirement.
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Critical care medicine · Jan 1998
Clinical TrialAerosolized antibiotics in mechanically ventilated patients: delivery and response.
To determine whether aerosolized antibiotics can be delivered efficiently to the lower respiratory tract in mechanically ventilated patients and to define possible clinical responses to these agents. ⋯ Nebulizer delivery of aerosolized aminoglycosides is efficient and predictable. In our clinical model, aerosolized antibiotics can make a significant impact on respiratory secretions. Their efficacy in treatment of critically ill patients remains to be determined.