Critical care medicine
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Critical care medicine · Dec 1999
Randomized Controlled Trial Multicenter Study Clinical TrialRisk factors for clinically important upper gastrointestinal bleeding in patients requiring mechanical ventilation. Canadian Critical Care Trials Group.
To evaluate the incidence and risk factors for clinically important upper gastrointestinal bleeding in critically ill patients requiring mechanical ventilation. ⋯ In critically ill ventilated patients, renal failure was independently associated with an increased risk of clinically important gastrointestinal bleeding, whereas enteral nutrition and stress ulcer prophylaxis with ranitidine conferred significantly lower bleeding rates.
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Critical care medicine · Dec 1999
Multicenter Study Clinical Trial Controlled Clinical TrialLong-term follow-up of survivors of acute lung injury: lack of effect of a ventilation strategy to prevent barotrauma.
To determine the effect of a ventilation strategy to prevent barotrauma on long-term outcome in survivors of acute lung injury. ⋯ We found that 1-2 yrs after the onset of their illness, survivors of acute lung injury have reductions in quality of life and exercise tolerance which are similar to patients with chronic diseases. We were unable to show that a limited ventilation strategy improves either long-term pulmonary function or quality of life in survivors of acute lung injury.
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Critical care medicine · Dec 1999
Randomized Controlled Trial Comparative Study Clinical TrialComparison of two semicontinuous cardiac output pulmonary artery catheters after valvular surgery.
To compare semicontinuous cardiac output (CCO) with bolus cardiac output (BCO), in the immediate postoperative period after valvular surgery, under hypothermic cardiopulmonary bypass with two CCO pulmonary artery catheters, based on the pulsed warm thermodilution technique, i.e., Opti-Q from Abbott or IntelliCath from Baxter-Edwards (Abbott and Baxter groups, respectively). ⋯ This study, during the immediate postoperative period in valvular surgery under hypothermic cardiopulmonary bypass, showed a satisfactory correlation between CCO and BCO with the two systems.
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Critical care medicine · Dec 1999
Meta AnalysisImmunonutrition in the critically ill: a systematic review of clinical outcome.
To perform a meta-analysis addressing whether enteral nutrition with immune-enhancing feeds benefits critically ill patients after trauma, sepsis, or major surgery. ⋯ The benefits of enteral immunonutrition were most pronounced in surgical patients, although they were present in all groups. The reduction in hospital length of stay and infections has resource implications.
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Critical care medicine · Dec 1999
Randomized Controlled Trial Comparative Study Clinical TrialA randomized comparison of ketorolac tromethamine and morphine for postoperative analgesia in critically ill children.
To evaluate the efficacy of a single dose of ketorolac compared with morphine for the relief of pain in children, and to determine the safety of ketorolac. ⋯ Ketorolac is comparable to morphine in relief of postoperative pain in children. A single dose of ketorolac does not result in abnormal postoperative bleeding or alter renal function. However, ketorolac may cause nausea and vomiting in some patients.