Critical care medicine
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Critical care medicine · Dec 1999
Gut mucosal-arterial Pco2 gradient as an indicator of splanchnic perfusion during systemic hypo- and hypercapnia.
By accounting for influences of systemic acid-base disturbances, gut mucosal-arterial Pco2 gradient (Pico2 - Paco2) has been increasingly advocated as a more specific marker of splanchnic perfusion than Pico2 alone. We examined the stability of the Pico2 - Paco2 gradient compared with raw Pico2 measurements during induced systemic hypo- and hypercapnia. ⋯ In this model of maintained portal blood flow, Pico2 - Paco2 remained essentially stable after hypoventilation but increased significantly after inducing hyperventilation. Our findings warrant cautious interpretation of Pico2 - Paco2 as an indicator of splanchnic perfusion during systemic hypocapnia.
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Critical care medicine · Dec 1999
Comment Letter Case ReportsProtein C in the treatment of coagulopathy in meningococcal sepsis.
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Critical care medicine · Dec 1999
Comment Letter Biography Historical ArticleAnother European view: the origin of pulmonary artery catheterization.