Critical care medicine
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To evaluate the therapeutic effects of activated protein C in an animal model of heat stroke. ⋯ The results indicate that systemic delivery of human recombinant activated protein C at the time point of onset of heat stroke may improve survival by ameliorating systemic inflammation, hypercoagulable state, and tissue ischemia and injury in multiple organs.
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Critical care medicine · Jul 2006
Editorial CommentBeyond sepsis: activated protein C and heat stroke.