Critical care medicine
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Critical care medicine · Apr 2013
Sepsis-surviving mice are more susceptible to a secondary kidney insult.
It is well known that sepsis causes damage in different organs, including kidneys. However, few studies have been conducted on the magnitude of the long-term effects of sepsis on the surviving population, in particular, in relation to kidney disease. In this study, we examined the impact of long-term effects of sepsis on a second kidney insult. ⋯ These results suggest that sepsis induces long-term effects in kidney structure aggravating tubule damage in a second kidney insult.