Critical care medicine
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Critical care medicine · Jul 2023
Observational StudyLimiting Dynamic Driving Pressure in Patients Requiring Mechanical Ventilation.
Previous studies reported an association between higher driving pressure (∆P) and increased mortality for different groups of mechanically ventilated patients. However, it remained unclear if sustained intervention on ∆P, in addition to traditional lung-protective ventilation, improves outcomes. We investigated if ventilation strategies limiting daily static or dynamic ∆P reduce mortality compared with usual care in adult patients requiring greater than or equal to 24 hours of mechanical ventilation. ⋯ Limiting either static or dynamic ∆P can further reduce the mortality of patients requiring mechanical ventilation.
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Critical care medicine · Jul 2023
Observational StudyAssociation of Sublingual Microcirculation Parameters and Capillary Refill Time in the Early Phase of ICU Admission.
This observational study was conducted to investigate capillary refill time (CRT) during the early phase of ICU admission in relationship with microvascular flow alteration and outcome in critically ill patients. ⋯ In our ICU population, a single-spot prolonged CRT was independently associated with abnormal microcirculation and increased mortality.