Critical care medicine
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Critical care medicine · Aug 2022
Meta AnalysisProbiotics in Critical Illness: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.
To determine the safety and efficacy of probiotics or synbiotics on morbidity and mortality in critically ill adults and children. ⋯ Low certainty RCT evidence suggests that probiotics or synbiotics during critical illness may reduce VAP, HAP, ICU and hospital LOS but probably have no effect on mortality.
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Critical care medicine · Aug 2022
Outcomes After Direct Discharge Home From Critical Care Units: A Population-Based Cohort Analysis.
To compare health service use and clinical outcomes for patients with and without direct discharge to home (DDH) from ICUs in Ontario. ⋯ There was no difference in outcomes for patients DDH compared with ward transfer prior to discharge when two approaches were used to minimize confounding within a large health systemwide observational cohort. We did not evaluate how patients are selected for DDH. Our results suggest that with careful patient selection, this practice might be feasible for routine implementation to ensure efficient and safe use of limited healthcare resources.