Critical care medicine
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Critical care medicine · Jul 2021
Exploring Patients' Perceptions on ICU Diaries: A Systematic Review and Qualitative Data Synthesis.
This study aims to summarize the current qualitative evidence on patients' experiences of reading the ICU diaries. ⋯ This qualitative synthesis shows that patients recommend having an ICU diary, enlightening benefits such as better coping with the slow recovery from critical illness, strengthening family ties, and humanizing the ICU staff. It also identifies characteristics of the diary valued by the patients, in order to standardize the ICU diary according to their perspectives, and allowing future comparability between randomized controlled trials.
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Critical care medicine · Jul 2021
Plasma Nucleosomes Are Associated With Mortality in Pediatric Acute Respiratory Distress Syndrome.
Circulating nucleosomes and their component histones have been implicated as pathogenic in sepsis and acute respiratory distress syndrome in adults. However, their role in pediatric acute respiratory distress syndrome is unknown. ⋯ Plasma nucleosomes are associated with acute respiratory distress syndrome severity, nonpulmonary organ failures, and worse outcomes in pediatric acute respiratory distress syndrome.
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Critical care medicine · Jul 2021
Determining the Electronic Signature of Infection in Electronic Health Record Data.
Recent sepsis studies have defined patients as "infected" using a combination of culture and antibiotic orders rather than billing data. However, the accuracy of these definitions is unclear. We aimed to compare the accuracy of different established criteria for identifying infected patients using detailed chart review. ⋯ Published criteria have a wide range of accuracy for identifying infected patients, with the Sepsis-3 criteria being the most sensitive and Rhee criteria being the most specific. These findings have important implications for studies investigating the burden of sepsis on a local and national level.