Critical care medicine
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Critical care medicine · Dec 1997
Perflubron decreases inflammatory cytokine production by human alveolar macrophages.
To determine whether inflammatory cytokine production by stimulated human alveolar macrophages is affected by perflubron exposure. ⋯ Exposure of stimulated human alveolar macrophages to perflubron in vitro decreases cytokine production. This observation suggests that perflubron may have anti-inflammatory activity.
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Critical care medicine · Dec 1997
Early bloodstream infection after cardiopulmonary bypass: frequency rate, risk factors, and implications.
To determine the incidence, predisposing factors, and outcome of early bloodstream infection after cardiopulmonary bypass. ⋯ Early bloodstream infection after cardiac surgery is uncommon and involves predominantly Gram-negative bacteria. The risk factors associated with bloodstream infection were preoperative morbidity and more complex surgery. Bloodstream infection was associated with a significantly adverse impact on outcome after cardiac surgery.
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Critical care medicine · Nov 1997
Comparative Study Clinical TrialComparison of simultaneously obtained arterial and capillary blood gases in pediatric intensive care unit patients.
To determine whether capillary blood gas measurements provide a clinically acceptable estimate of arterial pH, PCO2, and PO2. ⋯ Capillary blood gases accurately reflect arterial pH and PCO2 in most pediatric intensive care unit patients. Capillary samples did not significantly underestimate arterial hypercarbia or acidosis. This conservative reflection of metabolic status may be particularly useful in hemodynamically stable patients with mild-to-moderate lung disease.