Journal of Korean medical science
-
J. Korean Med. Sci. · Mar 2013
Bronchial anthracofibrosis and macroscopic tissue pigmentation on EBUS-TBNA predict a low probability of metastatic lymphadenopathy in Korean lung cancer patients.
The identification of mediastinal lymph nodes (LNs) in lung cancer is an important step of treatment decision and prognosis prediction. The endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) is widely used to assess the mediastinal LNs and tissue confirmation in lung cancer. As use of bronchoscopy or EBUS-TBNA has been increased, bronchial anthracofibrosis (BAF) has been detected frequently. ⋯ The adjusted odds ratio for predicting malignant LN was 0.46 for BAF, and 0.22 for macroscopic tissue pigmentation. The specificity of BAF and macroscopic tissue pigmentation for predicting a malignant LN was 75.7% and 42.2%, respectively, which was higher than the specificity of using LN size or standard uptake value on PET. In conclusion, BAF and macroscopic tissue pigmentation during EBUS-TBNA are less commonly found in malignant LNs than reactive LNs in Korean lung cancer patients.
-
J. Korean Med. Sci. · Mar 2013
Sudden infant death syndrome in Korea: a retrospective analysis of autopsy-diagnosed cases.
This study aimed to elucidate the demographic and sleeping environmental factors associated with sudden infant death syndrome (SIDS) in Korea. The autopsy reports of all SIDS cases reported to the National Forensic Service and Seoul National University College of Medicine between 1996 and 2008 were reviewed for data collection and analysis to identify the risk factors for SIDS. Analysis of the 355 SIDS cases reported within the study period revealed that of the 168 (47.3%) cases for which sleeping position before death had been reported, 75 (44.7%) cases had occurred after placement in prone or side position. ⋯ Analysis of the results indicated no tendency toward an increase or decrease in the use of a prone or side position. Rather, there was a statistically significant increasing trend for bed-sharing over the study period (OR, 1.087; 95% CI, 1.004-1.177; P = 0.04). These findings indicate the need for nationwide educational programs promoting a safe sleeping environment to enhance SIDS prevention.
-
J. Korean Med. Sci. · Mar 2013
Reference values for the pulmonary function of Korean adults using the data of Korea National Health and Nutrition Examination Survey IV (2007-2009).
The objective of this study was to develop new spirometric reference equations for the Korean population using the raw data of the fourth Korea National Health and Nutrition Examination Survey (KNHANES IV, 2007-2009). A total of 4,753 healthy lifelong nonsmokers without respiratory diseases and symptoms were selected as the reference population. ⋯ The newly developed reference equations for spirometry parameters were as follows: FEV1 (L) = -0.00025410 × (Age [years])(2) + 0.00012644 × (Height [cm])(2) - 0.00262 × Weight (kg) + 0.61493 (Men); FEV1 (L) = -0.00017538 × Age(2) + 0.00009598 × Height(2) - 0.00231 × Weight + 0.46877 (Women); FVC (L) = -0.00000219 × Age(3) + 0.0000006995642 × Height(3) + 1.19135 (Men); FVC (L) = 0.0167 × Age - 0.00030284 × Age(2) + 0.0000005850287 × Height(3) + 0.77609 (Women); FEV1/FVC (%) = -0.00289 × Age(2) - 0.16158 × Height(3) + 114.13736 (Men); FEV1/FVC (%) = -0.21382 × Age - 0.00000143 × Height(3) + 97.62514 (Women). The newly developed spirometric reference equation in this study can be used as criteria for the interpretation of spirometry results and the diagnosis of respiratory diseases in Korean adults.