Palliative medicine
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Palliative medicine · Mar 2008
Case ReportsOpioid withdrawal syndrome on switching from hydromorphone to alfentanil.
Opioid switching is increasingly practiced. This patient did not tolerate morphine, oxycodone or hydromorphone due to opioid toxicity. ⋯ Administration of small aliqouts of this drug reversed the symptoms. The existance of incomplete cross tolerance between hydromorphone and alfentanil is demonstrated.