Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association
-
Nephrol. Dial. Transplant. · Dec 2014
Prediction of membranous nephropathy recurrence after transplantation by monitoring of anti-PLA2R1 (M-type phospholipase A2 receptor) autoantibodies: a case series of 15 patients.
The predictive value of anti-M-type phospholipase A2 receptor (PLA2R1) autoantibodies for membranous nephropathy (MN) recurrence after renal transplantation remains controversial. ⋯ The monitoring of IgG4 anti-PLA2R1 titres during follow-up helps to predict MN recurrence, and a strong immunosuppressive treatment of anti-PLA2R1 positive patients may prevent recurrence.
-
Nephrol. Dial. Transplant. · Nov 2014
Randomized Controlled Trial Multicenter StudyDerivation and validation of cutoffs for clinical use of cell cycle arrest biomarkers.
Acute kidney injury (AKI) remains a deadly condition. Tissue inhibitor of metalloproteinases (TIMP)-2 and insulin-like growth factor binding protein (IGFBP)7 are two recently discovered urinary biomarkers for AKI. We now report on the development, and diagnostic accuracy of two clinical cutoffs for a test using these markers. ⋯ Clintrials.gov # NCT01209169 (Sapphire) and NCT01846884 (Opal).
-
Nephrol. Dial. Transplant. · Nov 2014
Randomized Controlled Trial Multicenter StudyFIND-CKD: a randomized trial of intravenous ferric carboxymaltose versus oral iron in patients with chronic kidney disease and iron deficiency anaemia.
The optimal iron therapy regimen in patients with non-dialysis-dependent chronic kidney disease (CKD) is unknown. ⋯ NCT00994318.