Alimentary pharmacology & therapeutics
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Aliment. Pharmacol. Ther. · Nov 2005
Randomized Controlled Trial Comparative StudyEffects of ferrous sulphate and non-ionic iron-polymaltose complex on markers of oxidative tissue damage in patients with inflammatory bowel disease.
Iron deficiency is a common complication of inflammatory bowel disease. Oral iron therapy may reinforce intestinal tissue injury by catalyzing production of reactive oxygen species. ⋯ Ferrous sulphate increased plasma malondialdehyde, a marker of lipid peroxidation. Comparing treatment with ferrous sulphate and iron-polymaltose complex, changes in plasma malondialdehyde tended to differ. Clinical disease activity was unchanged after both treatments.
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Aliment. Pharmacol. Ther. · Nov 2005
Comparative StudyAerophagia in adults: a comparison with functional dyspepsia.
Aerophagia is a functional upper gastrointestinal disorder that has not previously been well described in a large patient group. ⋯ Individuals with aerophagia experience prolonged upper gastrointestinal symptoms. Initial presenting symptoms appear to be distinctly different from those who have functional dyspepsia.