Brain injury : [BI]
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Brain injury : [BI] · Jan 2014
Randomized Controlled Trial Comparative StudySingle versus bilateral external ventricular drainage for intraventricular fibrinolysis using urokinase in severe ventricular haemorrhage.
Intraventricular fibrinolysis (IVF) through bilateral external ventricular drains (EVD) may provide better access of the thrombolytic agent to the intraventricular clot, potentially leading to faster clot clearance. ⋯ The results provide some evidence to support the use of bilateral EVDs for IVF in patients with severe IVH.
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Brain injury : [BI] · Jan 2014
Increased levels of interleukin-6, -8 and -10 are associated with fatal outcome following severe traumatic brain injury.
Despite the involvement of cytokine production in neurotrauma, there is still controversy regarding cytokines levels and clinical outcome following severe traumatic brain injury (TBI). ⋯ The findings indicate that increased IL-10, -8 and -6 levels may constitute an early predictor of unfavourable outcome in severe TBI patients.
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Brain injury : [BI] · Jan 2014
Adjusting to persistent post-concussive symptoms following mild traumatic brain injury and subsequent psycho-educational intervention: a qualitative analysis in military personnel.
Best practice guidelines outline ways in which mild traumatic brain injury (mTBI) and persistent post-concussive symptoms (PPCS) should be managed. In line with the existing evidence base, DMRC Headley Court established a treatment programme for UK servicemen and women with mTBI. This study explored the experiences of a sample of UK military personnel living with PPCS, who also received psycho-educational intervention (Phase 2) at this unit. ⋯ Following a flexible and tailored intervention for PPCS, patients report feeling empowered and describe having a renewed sense of stability.
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Brain injury : [BI] · Jan 2014
Comparative StudyInterpretation of magnetic resonance imaging in the chronic phase of traumatic brain injury: what is missed in the original reports?
To find eventual differences in detecting the late stage TBI findings in MRI between two neuroradiologists and to compare the results with the original reports. ⋯ The interpretation of TBI findings in late stage MRI yields significant variability between neuroradiologists. This may endanger diagnostics and lead to false treatment decisions and medico-legal problems. Standardized quantitative imaging analysis programs and advances in MRI technology should be utilized to improve radiological TBI diagnosis.
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Brain injury : [BI] · Jan 2014
Deaths due to traumatic brain injury in Austria between 1980 and 2012.
To investigate changes in TBI mortality in Austria during 1980-2012 and to identify causes for these changes. ⋯ These findings warrant better prevention of falls in the elderly and of suicides.