Journal of clinical epidemiology
-
Review Comparative Study
Head-to-head randomized trials are mostly industry sponsored and almost always favor the industry sponsor.
To map the current status of head-to-head comparative randomized evidence and to assess whether funding may impact on trial design and results. ⋯ The literature of head-to-head RCTs is dominated by the industry. Industry-sponsored comparative assessments systematically yield favorable results for the sponsors, even more so when noninferiority designs are involved.
-
The objective of the study was to assess the association between Grading of Recommendations Assessment, Development and Evaluation (GRADE) factors and the strength of recommendations. ⋯ The results showed that quality of evidence is a key determinant for making a strong vs. a weak recommendation.
-
Volume is an important feature in the evaluation of hypertrophic scars and keloids. Three-dimensional (3D) stereophotogrammetry is a noninvasive technique for the measurement of scar volume. This study evaluated the reliability and validity of 3D stereophotogrammetry for measuring scar volume. ⋯ Three-dimensional stereophotogrammetry is suitable for the use in clinical research but not for the follow-up of the individual patient.
-
To systematically review reports that queried abstract authors about reasons for not subsequently publishing abstract results as full-length articles. ⋯ Across medical specialties, the main reasons for not subsequently publishing an abstract in full lie with factors related to the abstract author rather than with journals.