European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery
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Eur J Cardiothorac Surg · Jan 1997
Randomized Controlled Trial Comparative Study Clinical TrialComplement and neutrophil activation during cardiopulmonary bypass: a randomized comparison of hypothermic and normothermic circulation.
Activation of both complement and neutrophils has been demonstrated to be involved in many pathological reactions following cardiopulmonary bypass (CPB). The aim of the present study is to evaluate the effect of normothermic and hypothermic CPB on both complement and neutrophil activation. ⋯ In conclusion, our study clearly demonstrates that warm CPB is associated with an increased ability to activate complement and neutrophils in patients undergoing coronary surgery.
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Eur J Cardiothorac Surg · Jan 1997
Aprotinin and deep hypothermic circulatory arrest: there are no benefits even when appropriate amounts of heparin are given.
To evaluate retrospectively the effect of 'high-dose' aprotinin on blood losses, donor blood requirements and morbid events on patients undergoing ascending aorta and/or aortic arch procedures with the employ of deep hypothermic circulatory arrest (HCA). ⋯ Even when appropriate amounts of heparin are administered, 'high-dose' aprotinin probably is not an effective blood-sparing drug in deep HCA. Aprotinin should be employed cautiously in this clinical setting because of its possible correlation with an increased rate of postoperative morbid events.
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Eur J Cardiothorac Surg · Jan 1997
Comparative StudyComparison of myocardial revascularization without cardiopulmonary bypass to standard open heart technique in patients with left ventricular dysfunction.
To compare myocardial revascularization without cardiopulmonary bypass to standard open heart technique in patients with left ventricular (LV) dysfunction. ⋯ These results show a trend for lower operative risk resulting in better overall survival in selected patients with LV dysfunction undergoing coronary artery bypass surgery without cardiopulmonary bypass.
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Eur J Cardiothorac Surg · Jan 1997
Comparative StudyGastroepiploic artery coronary bypass graft: non-invasive patency evaluation using color and duplex Doppler ultrasonography.
Color and duplex Doppler ultrasound and digital subtraction angiography were compared for the evaluation of graft patency of the gastroepiploic artery (GEA). ⋯ We propose ultrasound as a primary screening tool for evaluating graft patency. While color Doppler is a suitable technique for graft visualization, spectral analysis with the calculation of a cRI is required for functional evaluation.
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Eur J Cardiothorac Surg · Jan 1997
Reoperative coronary artery bypass procedures: risk factors for early mortality and late survival.
The number of coronary artery disease reoperations is increasing. The aim of this paper is to identify risk factors and evaluate the results of REDO coronary artery bypass grafting (CABG). ⋯ Reoperative CABG is effective, but has an increased operative mortality and morbidity. The long-term results are encouraging. Unstable angina, poor preoperative left ventricular function, renal insufficiency, insulin dependant diabetes and an interval shorter than 1 year of the initial operation were independent riskfactors for mortality.