Gynecologic oncology
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Gynecologic oncology · Sep 2006
Case ReportsEn bloc resection of diaphragm with lung for recurrent ovarian cancer: a case report.
Multiple series have demonstrated the feasibility of full-thickness diaphragm resection for ovarian cancer metastatic to the diaphragm. However, direct extension of tumor into the lung is sometimes encountered, and successful resection of this type of implant has not been previously described in the gynecologic oncology literature. ⋯ En bloc full-thickness diaphragm resection including a portion of lung tissue using the EndoGIA stapler is a safe, feasible, and effective method to optimize cytoreduction with disease-free margins in the context of invasive diaphragmatic ovarian cancer metastasis.
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Gynecologic oncology · Aug 2006
Effective palliative radiotherapy for symptomatic recurrent or residual ovarian cancer.
To evaluate the efficacy of radiotherapy (RT) for symptomatic recurrent or residual ovarian cancer. ⋯ Radiotherapy is highly effective in palliating symptomatic ovarian cancer. Excellent results are achieved for patients presenting with bleeding or pain. Symptomatic patients should be strongly considered for palliative radiotherapy. Higher doses of radiotherapy should be considered for those with symptoms other than bleeding or pain and those with longer life expectancies.
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Gynecologic oncology · Jun 2006
EditorialSexual rehabilitation medicine in a female oncology setting.
Comprehensive oncological care has recently expanded not only to include diagnosis and treatment but survivorship medicine as well. Tertiary health care facilities are now developing multidisciplinary survivorship programs that focus on helping cancer patients live active, fulfilled lives while dealing with the potentially damaging and longstanding sexual ramifications of cancer and cancer therapy. As part of a growing trend, health care institutions are establishing specialized sexual health programs to address cancer patients' sexual needs using functionalized survivorship curricula. ⋯ Using the Sexual Health Program at the Memorial Sloan-Kettering Cancer Center as a prototype for the development of future sexual health programs, this article will discuss the specific components and benefits of such programs. An effective program focuses on 4 key issues-clinical care, patient education and support, medical and scientific research, and medical education and training for health care professionals and providers. This article will discuss how sexual health programs benefit the female cancer patient (it should be noted, however, that these programs, such as the one at our institution, are usually available for either sex).
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Gynecologic oncology · Jun 2006
Comparative StudyEffectiveness of darbepoetin alfa versus epoetin alfa for the treatment of chemotherapy induced anemia in patients with gynecologic malignancies.
Chemotherapy induced anemia (CIA) commonly occurs in gynecologic oncology patients. This often leads to treatment with erythropoietic stimulating agents in order to prevent chemotherapy delays, dose modifications and transfusion of red blood cells. Our objective was to determine the subsequent transfusion rates following administration of either darbepoetin alfa or epoetin alfa. ⋯ This retrospective analysis powered to detect differences in transfusion rates revealed a statistically significant difference in transfusion rates between darbepoetin alfa and epoetin alfa for the treatment of CIA. These data warrant a randomized prospective trial in gynecologic oncology patients with careful attention to the timing of initiation of treatment, dosing regimens, and titration of growth factor.
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Gynecologic oncology · May 2006
Case ReportsMalignant acanthosis nigricans, tripe palms and the sign of Leser-Tre'lat, a hint to the diagnosis of early stage ovarian cancer: a case report and review of the literature.
Malignant acanthosis nigricans is a mucocutaneous eruption associated with internal malignancies. Tripe palms refers to a characteristic velvety thickening of the palms, with exaggeration of normal skin markings. The sign of Leser-Tre'lat is the presence of multiple seborrheic keratoses and scattered skin tags caused by a malignancy. We are reporting the first case of ovarian cancer in association with three coexisting cutaneous paraneoplastic dermatosis. ⋯ The presence of acanthosis nigricans in conjunction with tripe palms and the sign of Leser-Tre'lat are highly suggestive of an internal malignancy and necessitate an extensive investigation in order to discover the underlying malignancy.