BMJ : British medical journal
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Randomized Controlled Trial Clinical Trial
Primary care based randomised, double blind trial of amoxicillin versus placebo for acute otitis media in children aged under 2 years.
To determine the effect of antibiotic treatment for acute otitis media in children between 6 months and 2 years of age. ⋯ Seven to eight children aged 6 to 24 months with acute otitis media needed to be treated with antibiotics to improve symptomatic outcome at day four in one child. This modest effect does not justify prescription of antibiotics at the first visit, provided close surveillance can be guaranteed.