BMJ : British medical journal
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Dietary calcium intake and risk of fracture and osteoporosis: prospective longitudinal cohort study.
To investigate associations between long term dietary intake of calcium and risk of fracture of any type, hip fractures, and osteoporosis. ⋯ Gradual increases in dietary calcium intake above the first quintile in our female population were not associated with further reductions in fracture risk or osteoporosis.
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To investigate the impact of industry funding on reporting of subgroup analyses in randomised controlled trials. ⋯ Industry funded randomised controlled trials, in the absence of statistically significant primary outcomes, are more likely to report subgroup analyses than non-industry funded trials. Industry funded trials less frequently prespecify subgroup hypotheses and less frequently test for interaction than non-industry funded trials. Subgroup analyses from industry funded trials with negative results for the primary outcome should be viewed with caution.
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Randomized Controlled Trial
Effect of using reporting guidelines during peer review on quality of final manuscripts submitted to a biomedical journal: masked randomised trial.
To investigate the effect of an additional review based on reporting guidelines such as STROBE and CONSORT on quality of manuscripts. ⋯ Additional reviews based on reporting guidelines improve manuscript quality, although the observed effect was smaller than hypothesised and not definitively demonstrated. Authors adhere more to suggestions from conventional reviews than to those from additional reviews, showing difficulties in adhering to high methodological standards at the latest research phases. To boost paper quality and impact, authors should be aware of future requirements of reporting guidelines at the very beginning of their study. Trial registration and protocol Although registries do not include trials of peer review, the protocol design was submitted to sponsored research projects (Instituto de Salud Carlos III, PI081903).