BMJ : British medical journal
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This very large cohort study demonstrated an association between use of intermediate-duration NMBD and risk of postoperative desaturation and reintubation requiring ICU admission, and a similar association with these outcomes and neostigmine reversal.
Qualitative neuromuscular monitoring did not reduce this risk.
Study population was all patients at Massachusetts General Hospital undergoing general anaesthesia including a muscle relaxant over a 4 year period, and who were extubated at the end of the procedure.
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Review Meta Analysis
Physiotherapy intervention in Parkinson's disease: systematic review and meta-analysis.
To assess the effectiveness of physiotherapy compared with no intervention in patients with Parkinson's disease. ⋯ Physiotherapy has short term benefits in Parkinson's disease. A wide range of physiotherapy techniques are currently used to treat Parkinson's disease, with little difference in treatment effects. Large, well designed, randomised controlled trials with improved methodology and reporting are needed to assess the efficacy and cost effectiveness of physiotherapy for treating Parkinson's disease in the longer term.
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Review Meta Analysis
Cutaneous melanoma attributable to sunbed use: systematic review and meta-analysis.
To estimate the burden of melanoma resulting from sunbed use in western Europe. ⋯ Sunbed use is associated with a significant increase in risk of melanoma. This risk increases with number of sunbed sessions and with initial usage at a young age (<35 years). The cancerous damage associated with sunbed use is substantial and could be avoided by strict regulations.