BMJ : British medical journal
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Review Meta Analysis
Calcium intake and bone mineral density: systematic review and meta-analysis.
To determine whether increasing calcium intake from dietary sources affects bone mineral density (BMD) and, if so, whether the effects are similar to those of calcium supplements. ⋯ Increasing calcium intake from dietary sources or by taking calcium supplements produces small non-progressive increases in BMD, which are unlikely to lead to a clinically significant reduction in risk of fracture.
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Review Meta Analysis
Risk of recurrent stillbirth: systematic review and meta-analysis.
To determine the risk of recurrent stillbirth. ⋯ The risk of stillbirth in subsequent pregnancies is higher in women who experience a stillbirth in their first pregnancy. This increased risk remained after adjusted analysis. Evidence surrounding the recurrence risk of unexplained stillbirth remains controversial.
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Review Meta Analysis
Methotrexate use and risk of lung disease in psoriasis, psoriatic arthritis, and inflammatory bowel disease: systematic literature review and meta-analysis of randomised controlled trials.
To evaluate the relative risk of pulmonary disease among patients with psoriasis, psoriatic arthritis, and inflammatory bowel disease treated with methotrexate. ⋯ Findings suggested that there was no increased risk of lung disease in methotrexate treated patients with non-malignant inflammatory diseases. Given the limitations of the study, however, we cannot exclude a small but clinically important risk.
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Review Meta Analysis
Risk of neuropsychiatric adverse events associated with varenicline: systematic review and meta-analysis.
To determine the risk of neuropsychiatric adverse events associated with use of varenicline compared with placebo in randomised controlled trials. ⋯ PROSPERO 2014:CRD42014009224.
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Review Meta Analysis
Multidisciplinary biopsychosocial rehabilitation for chronic low back pain: Cochrane systematic review and meta-analysis.
To assess the long term effects of multidisciplinary biopsychosocial rehabilitation for patients with chronic low back pain. ⋯ Multidisciplinary biopsychosocial rehabilitation interventions were more effective than usual care (moderate quality evidence) and physical treatments (low quality evidence) in decreasing pain and disability in people with chronic low back pain. For work outcomes, multidisciplinary rehabilitation seems to be more effective than physical treatment but not more effective than usual care.