Medical principles and practice : international journal of the Kuwait University, Health Science Centre
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Depression leads to behavioral and systemic changes making individuals more susceptible to inflammatory diseases. This study was conducted to assess the periodontal status of patients with clinically diagnosed mild and moderate depression. ⋯ Patients with moderate depression showed high periodontal destruction and inflammation as compared to those with mild depression. Further, deep pockets were associated with depressive patients. Periodontal care is required in such patients so that the progression of periodontal diseases can be prevented at the earliest.
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The aims of the study were to assess the prevalence of steatopygia on bone scintigraphy of obese patients and to evaluate its effect on the appearance of the lumbar spine, and the added benefit of single photon emission computed tomography (SPECT) and SPECT/computed tomography (SPECT/CT) in overcoming possible artifacts. ⋯ Steatopygia is common on bone scintigraphy of obese patients, higher in females and morbidly obese patients. Obesity-related artifacts in bone scintigraphy, including attenuation effect and edge artifact, are common in this patient group. SPECT or SPECT/CT improves the diagnostic accuracy by overcoming the effects of steatopygia seen on planar images.
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Large-cell lung carcinoma (LCLC) is generally poorly differentiated with a poor prognosis. This study aimed to explore the impact of chemotherapy on the prognosis of patients with stage II-IV LCLC and to construct nomograms to predict overall survival (OS) and cancer-specific survival (CSS). ⋯ Chemotherapy could improve the prognosis among stage II-IV LCLC patients. In addition, the nomograms showed good predictive ability, which could be useful in making clinical decisions.
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Seizures are common in palliative care patients and its control is essential in the management of these patients as it helps to reduce suffering at the end of life. Subcutaneous levetiracetam has been used off-license for seizure control in palliative care. ⋯ Subcutaneous levetiracetam was well tolerated and effective in controlling seizures in palliative care when oral administration or intravenous access was not an option. Randomized controlled trials are needed to elucidate the efficacy and tolerability of subcutaneous levetiracetam in clinical practice.
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Observational Study
Association of socioeconomic status and oral cancer mortality in Brazil: temporal trends and spatial distribution.
The objective of this observational study was to evaluate the relationship between the oral cancer mortality rate and socioeconomic indicators throughout the Brazilian territory, between 2010 and 2019. ⋯ Despite the higher number of oral cancer deaths in regions with higher social indices, increasing temporal trends are more accentuated in regions with lower socioeconomic levels.