Journal of internal medicine
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Inflammatory bowel disease in Hermansky-Pudlak syndrome: a retrospective single-centre cohort study.
Knowledge about inflammatory bowel disease (IBD) in patients with Hermansky-Pudlak syndrome (HPS), a rare autosomal recessive disorder characterized by defective biogenesis of lysosome-related organelles, could provide insights into IBD in general. ⋯ IBD resembling Crohn's disease affects some patients with HPS; genetic heterogeneity is a feature of HPS IBD. HPS3 is a new gene associated with human IBD. Very early-onset IBD can develop in HPS.
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The significance of chronic kidney disease on susceptibility to COVID-19 and subsequent outcomes remains unaddressed. ⋯ Renal insufficiency was associated with progressive increase in both rate of hospital-diagnosed COVID-19 and subsequent risk of adverse outcomes. Results underscore a possible vulnerability associated with impaired renal function in relation to COVID-19.
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To report the changes in volume and characteristics of medical activities in the Vatican City State during COVID-19 pandemic. ⋯ Medical activities of the Vatican City State have been severely impacted, especially during the first months of the pandemic. However, organizational efforts allowed rapid restoration to near-normal volumes.
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Observational Study
Assessment of Thirty-Day Readmission Rate, Timing, Causes, and Predictors after Hospitalization with COVID-19.
There are limited data on the characteristics of 30-day readmission after hospitalization with coronavirus disease 2019 (COVID-19). ⋯ With 4.5% of the thirty-day readmission rate, COVID-19 survivors were readmitted early after hospital discharge, mainly due to morbidities of COVID-19. One in five readmitted COVID-19 survivors died during their readmission.