Journal of anesthesia
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The stability of enflurane in soda lime was examined. A product of enflurane decomposition was detected after the reaction of enflurane with soda lime, but not in the absence of soda lime. ⋯ The same decomposition product was produced by the reaction of enflurane with potassium, sodium, or calcium hydroxides, and it was also detected in the gas phase at a maximum concentration of 1.29 ppm at 420 min after 5% enflurane circulated with 200 ml/min carbon dioxide gas in a closed anesthesia circle system with a soda lime canister and a model lung. We concluded that enflurane was decomposed to 1-chloro-1,2-difluorovinyl difluoromethyl ether by soda lime.