Journal of anesthesia
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Journal of anesthesia · Oct 2012
Randomized Controlled TrialReduction of pain on injection of propofol: combination of nitroglycerin and lidocaine.
Pain on propofol injection is a common adverse effect. This study examined the effect of a combination of nitroglycerin and lidocaine on pain during propofol injection compared to lidocaine alone. ⋯ A combination of nitroglycerin 0.1 μg/kg and lidocaine 20 mg with venous occlusion for 1 min was more effective than lidocaine 20 mg alone in decreasing pain during propofol injection.
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Journal of anesthesia · Oct 2012
Randomized Controlled Trial Multicenter StudyEffects of dose ranging of adenosine infusion on electrocardiographic findings during and after general anesthesia.
To assess changes in the electrocardiogram (ECG) associated with intraoperative infusion of adenosine in patients undergoing open abdominal gynecological surgery. ⋯ There was no difference in QTc prolongation following intraoperative administration of adenosine infusion compared with placebo during isoflurane general anesthesia. However, QTc prolongation is common following general anesthesia.
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Journal of anesthesia · Oct 2012
Randomized Controlled TrialBuprenorphine added to levobupivacaine enhances postoperative analgesia of middle interscalene brachial plexus block.
The aim of this study was to assess whether addition of epineural buprenorphine prolonged postoperative analgesia of middle interscalene brachial plexus block (MIB) with levobupivacaine. ⋯ Epineural buprenorphine prolonged postoperative analgesia of MIB more effectively than intramuscular buprenorphine, which suggests that buprenorphine acts at a peripheral nervous system site of action.