Journal of anesthesia
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Journal of anesthesia · Oct 2013
Case ReportsThird nerve palsy associated with preeclampsia and HELLP syndrome.
Preeclampsia can cause myriad organ dysfunction, including cranial nerve palsies that pose diagnostic and management dilemmas. We present an unusual case of third nerve palsy, (presenting as diplopia, ptosis) with hypertension, hyperreflexia, proteinuria, easy bruising in a parturient at 34 + 6/52 weeks of twins gestation. ⋯ Postoperatively, stroke, aneurysm and intra-cerebral causes of third nerve palsy were excluded, with subsequent recovery of symptoms upon blood pressure normalization. The eye signs are postulated to be due to two preeclamptic mechanisms involving disordered cerebral autoregulation: (1) hyperperfusion and breakdown of the blood-brain barrier that occurs with rising hypertension, causing fluid/blood product extravasation into brain parenchyma, or (2) focal reactive vasoconstriction and local hypoperfusion, contributed to by endothelial dysfunction.
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Journal of anesthesia · Oct 2013
Effects of battery type and age on performance of rechargeable laryngoscopes.
Optimal visualization of the glottis can be crucial to successful laryngoscopy. Limited information has been published on the light intensity delivered from laryngoscopes powered by rechargeable batteries. In this study the laryngoscope light intensity delivered from 10 nickel metal hydride (NiMH), 7 nickel cadmium (NiCAD), and 2 lithium (LI) batteries with 3-5 or more years of clinical usage were tested in comparison to 5 new NiMH batteries. ⋯ There were significant differences in the time to minimum light intensity among all groups (p = 0.00-0.04). All new and used batteries exceeded the minimum ISO standard of light intensity for more than 10 min. These data demonstrate that rechargeable laryngoscope batteries can safely be used for several years before requiring replacement.
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Journal of anesthesia · Oct 2013
Relationship between vascular reactivity and expression of HMGB1 in a rat model of septic aorta.
High mobility group box 1 (HMGB1), a ubiquitous nuclear protein, induces several inflammatory diseases and functions as a fatal factor when released extracellularly. The effect of HMGB1 on vascular reactivity during sepsis remains to be clarified. ⋯ The present results strongly suggest that HMGB1 plays an important role in vascular malfunction from an early phase of sepsis.